Ion Channel Blocker with high selectivity

Peptanova offers presently 36 different ion channel blocker including ten Conotoxin peptides, which build a dedicated peptide family. The offered ion channel blockers like SNX-482 , Iberiotoxin, Margatoxin or Kurtoxin are chemically manufactured peptides and not isolated from animal origin or made by recombinant technics.

New Ion channel blocker in 2011:
Neuronal Tetrodotoxin-Sensitive Na⁺-Channel Blocker Huwentoxin-IV (HWTX-IV)
T-Type Ca²⁺ Channel / Na⁺ Channel / K⁺ Channel Blocker ProTX-I and ProTX-II
Inhibitor of P2X3 Purinoreceptors Purotoxin-I

Mechanosensitive ion channels (MSCs) are ubiquitous from unicellular to multicellular organisms and participate in numerous physiological processes including touch and pain sensation, salt and fluid balance, blood pressure control, cell volume regulation, and turgor control [Physiol. Rev., 81, 685 (2001)]. Analysis of the functions mediated by these channels can be performed by utilizing a specific ion channel blocker with high selectivity to the particular channels.

Peptidic T-type Ca²⁺-Channel Blocker Voltage-dependent Ca²⁺-channels are classified according to the nature of their α1 subunits. N-type (Ca²⁺) calcium channel blockers are potent tools for research and development of alternative analgesic strategies. High voltage-activated channels (HVA) are composed of α1A-α1F/α1S, leading to L-, N-, P/Q- and R-type channels. Peptidic Ca²⁺ channel blockers like Agatoxin, Calciseptine, Calcicludine, SNX-482, Kurtoxin and Agelenin are specific for each channel and can be ordered easily direct from our stock.
PeptaNova offers many different K⁺ channel blockers like Charybdotoxin, Iberiotoxin, Stichodactyla Toxin or Margatoxin.

A great variety of channel blockers are available for prompt delivery from our store in Sandhausen. All items will be shipped at room temperature by courier service and will arrive immediately after your order. Please visit the following sites to get more information about the offered ion channel blocker peptides manufactured at Peptide Institute.

Show 1 to 10 (of total 30 products)

Sites: 1 2 3 [next]

ω-Agatoxin IVA

4256-s 0.1 mg
Lys - Lys - Lys - Cys - Ile - Ala - Lys - Asp - Tyr - Gly - Arg - Cys - Lys - Trp - Gly - Gly - Thr - Pro - Cys - Cys - Arg - Gly - Arg - Gly - Cys - Ile - Cys - Ser - Ile - Met - Gly - Thr - Asn - Cys - Glu - Cys - Lys - Pro - Arg - Leu - Ile - Met - Glu - Gly - Leu - Gly - Leu - Ala

245,00 EUR*

Biotinyl-ω-Agatoxin IVA

3402-s 0.1 mg
Biotinyl - Lys - Lys - Lys - Cys - Ile - Ala - Lys - Asp - Tyr - Gly - Arg - Cys - Lys - Trp - Gly - Gly - Thr - Pro - Cys - Cys - Arg - Gly - Arg - Gly - Cys - Ile - Cys - Ser - Ile - Met - Gly - Thr - Asn - Cys - Glu - Cys - Lys - Pro - Arg - Leu - Ile - Met - Glu - Gly - Leu - Gly - Leu - Ala

330,00 EUR*

ω-Agatoxin TK

4294-s 0.1 mg
Glu - Asp - Asn - Cys - Ile - Ala - Glu - Asp - Tyr - Gly - Lys - Cys - Thr - Trp - Gly - Gly - Thr - Lys - Cys - Cys - Arg - Gly - Arg - Pro - Cys - Arg - Cys - Ser - Met - Ile - Gly - Thr - Asn - Cys - Glu - Cys - Thr - Pro - Arg - Leu - Ile - Met - Glu - Gly - Leu - D-Ser - Phe - Ala

295,00 EUR*

Agelenin

4247-s 0.1 mg
Gly - Gly - Cys - Leu - Pro - His - Asn - Arg - Phe - Cys - Asn - Ala - Leu - Ser - Gly - Pro - Arg - Cys - Cys - Ser - Gly - Leu - Lys - Cys - Lys - Glu - Leu - Ser - Ile - Trp - Asp - Ser - Arg - Cys - Leu - NH₂

295,00 EUR*

Apamin

4257-v 0.5 mg
Cys - Asn - Cys - Lys - Ala - Pro - Glu - Thr - Ala - Leu - Cys - Ala - Arg - Cys - Gln - Gln - His-NH₂

145,00 EUR*

Calcicludine

4310-s 0.1 mg
Trp - Gln - Pro - Pro - Trp - Tyr - Cys - Lys - Glu - Pro - Val - Arg - Ile - Gly - Ser - Cys - Lys - Lys - Gln - Phe - Ser - Ser - Phe - Tyr - Phe - Lys - Trp - Thr - Ala - Lys - Lys - Cys - Leu - Pro - Phe - Leu - Phe - Ser - Gly - Cys - Gly - Gly - Asn - Ala - Asn - Arg - Phe - Gln - Thr - Ile - Gly - Glu - Cys - Arg - Lys - Lys -Cys - Leu - Gly - Lys

295,00 EUR*

Calciseptine

4255-s 0.1 mg
Arg - Ile - Cys - Tyr - Ile - His - Lys - Ala - Ser - Leu - Pro - Arg - Ala - Thr - Lys - Thr - Cys - Val - Glu - Asn - Thr - Cys - Tyr - Lys - Met - Phe - Ile - Arg - Thr - Gln - Arg - Glu - Tyr - Ile - Ser - Glu - Arg - Gly - Cys - Gly - Cys - Pro - Thr - Ala - Met - Trp - Pro - Tyr - Gln - Thr - Glu - Cys - Cys - Lys - Gly -Asp - Arg - Cys - Asn - Lys

295,00 EUR*

Charybdotoxin

4227-s 0.1 mg
Pyr - Phe - Thr - Asn - Val - Ser - Cys - Thr - Thr - Ser - Lys - Glu - Cys - Trp - Ser - Val - Cys - Gln - Arg - Leu - His - Asn - Thr - Ser - Arg - Gly - Lys - Cys - Met - Asn - Lys - Lys - Cys - Arg - Cys - Tyr - Ser

148,00 EUR*

Chlorotoxin

4282-v 0.5 mg
Met - Cys - Met - Pro - Cys - Phe - Thr - Thr - Asp - His - Gln - Met - Ala - Arg - Lys - Cys - Asp - Asp - Cys - Cys - Gly - Gly - Lys - Gly - Arg - Gly - Lys - Cys - Tyr - Gly - Pro - Gln - Cys - Leu - Cys - Arg - NH₂

410,00 EUR*

Dendrotoxin I

4330-s 0.1 mg
Pyr - Pro - Leu - Arg - Lys - Leu - Cys - Ile - Leu - His - Arg - Asp - Pro - Gly - Arg - Cys - Tyr - Gln - Lys - Ile - Pro - Ala - Phe - Tyr - Tyr - Asn - Gln - Lys - Lys - Lys - Gln - Cys - Glu - Gly - Phe - Thr - Trp - Ser - Gly - Cys - Gly - Gly - Asn - Ser - Asn - Arg - Phe - Lys - Thr - Ile - Glu - Glu - Cys - Arg - Arg - Thr - Cys - Ile - Arg - Lys

285,00 EUR*

Show 1 to 10 (of total 30 products)

Sites: 1 2 3 [next]