Arousal and anxiety-like behaviour are regulated by several modulators in the central nervous system, including classical neurotransmitters (i.e. noradrenaline) and peptides (i.e. orexin). in a recent paper, a new peptide named Neuropeptide S (NPS) has been identified as a novel modulator of wakefulness and anxienty. A novel hypothalamic peptide, which activates the orphan G protein-coupled receptors, GPR7 and GPR8 is called Neuropeptide W (NPW). The effects of NPW on feeding and energy expenditure in rats are described recently. Neuropeptide Y (NPY) is involved in the control of food intake and seems to be involved in circadian rhythms, sexual function and anxiety responses.
4403-v 0.5 mg Trp - Tyr - Lys - His - Val - Ala - Ser - Pro - Arg - Tyr - His - Thr - Val - Gly - Arg - Ala - Ala - Gly - Leu - Leu - Met - Gly - Leu - Arg - Arg - Ser - Pro - Tyr - Leu - Trp
4404-v 0.5 mg Trp - Tyr - Lys - His - Val - Ala - Ser - Pro - Arg - Tyr - His - Thr - Val - Gly - Arg - Ala - Ser - Gly - Leu - Leu - Met - Gly - Leu - Arg - Arg - Ser - Pro - Tyr - Leu - Trp
4158-s 0.1 mg | 4158-v 0.5 mg Tyr - Pro - Ser - Lys - Pro - Asp - Asn - Pro - Gly - Glu - Asp - Ala - Pro - Ala - Glu - Asp - Met - Ala - Arg - Tyr - Tyr - Ser - Ala - Leu - Arg - His - Tyr - Ile - Asn - Leu - Ile - Thr - Arg - Gln - Arg - Tyr - NH2
4162-s 0.1 mg | 4162-v 0.5 mg Tyr - Pro - Ser - Lys - Pro - Asp - Asn - Pro - Gly - Glu - Asp - Ala - Pro - Ala - Glu - Asp - Leu - Ala - Arg - Tyr - Tyr - Ser - Ala - Leu - Arg - His - Tyr - Ile - Asn - Leu - Ile - Thr - Arg - Gln - Arg - Tyr - NH2
4314-s 0.1 mg Tyr - Pro - Ser - Lys - Pro - Asp - Asn - Pro - Gly - Glu - Asp - Ala - Pro - Ala - Glu - Asp - Leu - Ala - Arg - Tyr - Tyr - Ser - Ala - Leu - Arg - His - Tyr - Ile - Asn - Leu - Leu - Thr - Arg - Pro - Arg - Tyr - NH2
4315-s 0.1 mg Pro - Ala - Glu - Asp - Leu - Ala - Arg - Tyr - Tyr - Ser - Ala - Leu - Arg - His - Tyr - Ile - Asn - Leu - Ile - Thr - Arg - Gln - Arg - Tyr - NH2
