Opioid peptides are small endogenic or exogenic poly peptides with distinct effects on the G-protein-coupled receptors (delta, kappa, mu) which are located in the central nervous system and peripheral tissues. The endogenous opioid peptides can be classified in two groups. The activity of the first group (enkephalins, endorphins, dynorphins) is based on the tetrapeptide sequence Tyr-Gly-Gly-Phe. The second group of Endomorphins is characterized by the tripeptide Tyr-Pro-Phe/Trp sequence. The study of the opioid peptide system may help to understand the mechanism of modulation of pain and may be a tool for the development of new effective substances for pain-control with a minimum of side effects. All Opioid peptides offered from PeptaNova are carefully synthesized by Peptide Institute Inc.
