Ac-Asp-Gln-Thr-Asp-AMC

85,00 € excl. 19% VAT

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Ac-Asp-Gln-Thr-Asp-AMC | Ac-DQTD-AMC

Ac-Asp-Gln-Thr-Asp-MCA | Ac-DQTD-MCA

3193-v 5 mg | 85.00 EUR

Acetyl- L-aspartyl- L-glutaminyl- L-threonyl- L-aspartic acid α-(4-methyl- coumaryl- 7- amide)

(M.W. 676.63) C29H36N6O13

Synthetic Product
A trace of impurity might be detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 2 %.

Selective Substrate for Caspase-3/7 (apopain; Yama; CPP-32)
(Deduced from the Cleavage Site of Focal Adhesion Kinase and Gelsolin)

References:

  1. L.-P. Wen, J.A. Fahrni, S. Troie, J.-L. Guan, K. Orth and G.D. Rosen, J. Biol. Chem., 272, 26056 (1997)
  2. S. Kothakota, T. Azuma, C. Reinhard, A. Klippel, J. Tang, K. Chu, T.J. McGarry, M.W. Kirschner, K. Koths, D.J. Kwiatkowski and L.T. Williams, Science, 278, 294 (1997)

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