Ac-Trp-Glu-His-Asp-H (aldehyde)

158,00 € excl. 19% VAT

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SKU: 3187-v Category: Tags: ,

Ac-WEHD-CHO | Ac-Trp-Glu-His-Asp-H (aldehyde)

3187-v 5 mg | 158.00 EUR

Acetyl- L- Tryptophyl- L- Glutamyl- L- Histidyl- l- Aspart- 1- al

(M.W. 611.61) C28H33N7O9 [189275-71-6]

Synthetic Tetrapeptide aldehyde (Trifluoroacetate Form)

Reversible Inhibitor for Caspase-1

The peptide sequence Ac-Trp-Glu-His-Asp-H is the best possible tetra peptide for a synthetic caspase-1 inhibitor. ICE inhibition with Ac-WEHD-CHO is reversible very effective.

References:

  1. T.A. Rano, T. Timkey, E.P. Peterson, J. Rotonda, D.W. Nicholson, J.W. Becker, K.T. Chapman and N.A. Thornberry, Chem. Biol., 4, 149 (1997)

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