Ac-Tyr-Val-Lys-Asp-H (aldehyde)

148,00  excl. 19% VAT

SKU: 3166-v Category:

Ac-YVKD-CHO | Ac-Tyr-Val-Lys-Asp-H (aldehyde)

3166-v 5 mg | 148.00 EUR

Acetyl- L- Tyrosyl- L- Valyl- L- Lysyl- L- Aspartinal

(M.W. 549.62) C26H39N5O8 [147821-01-1]

Synthetic Product (Trifluoroacetate Form)

Caspase-1 (ICE) Inhibitor – Slow-binding inhibitor, with low selectivity

The vial contains exactly 5.0 mg ( 9.0 µmol ) of the substrate Ac-YVKD-CHO, which has been lyophilized as an amorphous powder from aqueous solution.
Solution: Carefully open the cap. Pour 0.9 ml of DMSO* (analytical grade) into the vial. Close the cap tightly. Shake well until all the contents are dissolved. This procedure furnishes a 10 mM solution of the titled compound. *DMSO: dimethyl sulfoxide
Advice: Do not use an aqueous buffer solution substitute for DMSO. If an aqueous buffer solution is used, this compound may racemize soon. The DMSO solution is stable at -20″C for more than one month if it is protected from moisture and kept in the dark.

References:

  1. N.A. Thornberry et al, Nature, 356, 368 (1992)
  2. T.L. Graybill, R.E. Dolle, C.T. Helaszek, R.E. Miller, and M.A. Ator, Int. J. Pept. Protein Res., 44, 173 (1994)