Adropin (34-76)

225,00 € excl. 19% VAT

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SKU: 4456-s Category:

Adropin (34-76) (Human, Rat, Mouse)
Regulatory Factor in Energiy Homeostasis

4456-s 0.1 mg | 225.00 EUR/Vial

Synthetic Product (Disulfide bonds between Cys1-Cys23)

Cys – His – Ser – Arg – Ser – Ala – Asp – Val – Asp – Ser – Leu – Ser – Glu – Ser – Ser – Pro – Asn – Ser – Ser – Pro – Gly – Pro – Cys – Pro – Glu – Lys – Ala – Pro – Pro – Pro – Gln – Lys – Pro – Ser – His – Glu – Gly – Ser – Tyr – Leu – Leu – Gln – Pro

(M.W. 4499.8) C190H293N55O68S2

The purity of our synthetic peptide Adropin (34-76) (Human, Rat, Mouse) is guaranteed to be higher than 98% by HPLC

Adropin (34-76) (Human, Rat, Mouse) is a 76 mer polypeptide with one disulfid bridge. Disulfide bridged Adropin (34-76) was synthesized by solid phase peptide chemistry for biological tests; glucose homeostasis and hepatic lipidmetabolismn were improved in mouse with 90 or 900 nmol/kg/day through intraperitoneal administration. These effects were independent of adiposity or food intake. Adropin (34-76) (Human, Rat, Mouse) may be a powerful peptide tool in the study of obesity-associated hepatosteatosis and hyperinsulinemia.

References:

  1. K.G. Kumar, J.L. Trevaskis, D.D. Lam, G.M. Sutton, R.A. Koza, V.N. Chouljenko, K.G. Kousoulas, P.M. Rogers, R.A. Kesterson, M. Thearle, A.W. Ferrante, Jr., R.L. Mynatt, T.P. Burris, J.Z. Dong, H.A. Halem, M.D. Culler, L.K. Heisler, J.M. Stephens and A.A. Butler, Cell Metab., 8, 468 (2008) (Original, Primary Structure, Pharmacology)

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