Agelenin

220,00 € excl. 19% VAT

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SKU: 4247-s Category:

Agelenin
(Spider, Agelena opulenta)

4247-s 0.1 mg | 220.00 EUR

Synthetic Product (Disulfide bonds between Cys3-Cys19, Cys10-Cys24 and Cys18-Cys34

Gly – Gly – Cys – Leu – Pro – His – Asn – Arg – Phe – Cys – Asn – Ala – Leu – Ser – Gly – Pro – Arg – Cys – Cys – Ser – Gly – Leu – Lys – Cys – Lys – Glu – Leu – Ser – Ile – Trp – Asp – Ser – Arg – Cys – Leu – NH2

(M.W. 3818.4) C160H254N52O45S6

The purity is guaranteed to be higher than 99% by HPLC

Agelenin is a potent presynaptic Ca2+ Channel Antagonist, originally isolated from Spider, Agelena opulenta

The neuropeptide toxin Agelenin is of synthetic origin and is manufactured by Peptide Institute using modern peptide chemical procedures.

References:

  1. K. Hagiwara, T. Sakai, A. Miwa, N. Kawai and T. Nakajima, Biomed. Res. 11, 181 (1990) (Original)
  2. T. Inui, K. Hagiwara, K. Nakajima, T. Kimura, T. Nakajima and S. Sakakibara, Pep. Res., 5, 140 (1992) (Chem. Synthesis of Agelenin, S-S bond and amides)

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