Amylin (Human)

295,00 € excl. 19% VAT

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SKU: 4219-v Category:

Amylin (Human)
IAPP (Islet Amyloid Polypeptide) | DAP (Diabetes-Associated Peptide)

4219-v 0.5 mg | 295.00 EUR/Vial

Synthetic Product (Disulfide bonds between Cys2-Cys7)

Lys – Cys – Asn – Thr – Ala – Thr – Cys – Ala – Thr – Gln – Arg – Leu – Ala – Asn – Phe – Leu – Val – His – Ser – Ser – Asn – Asn – Phe – Gly – Ala – Ile – Leu – Ser – Ser – Thr – Asn – Val – Gly – Ser – Asn – Thr – Tyr – NH2

(M.W. 3903.3) C165H261N51O55S2 [122384-88-7]

The purity of Amylin (Human) is guaranteed to be higher than 97% by HPLC

Amylin (Human) is a 37 mer polypeptide with two disulfid bridges, which shows suplementary activities to insulin. This peptide hormone called Islet amyloid polypeptide (IAPP) or alternatively Amylin was secreted by pancreatic β-cells like insulin or glucagon depending to food intake.

References:

  1. P. Westermark, C. Wernstedt, E. Wilander, D.W. Hayden, T.D. O´Brian and K.H. Johnson, Proc. Natl. Acad. Sci. USA, 84, 3881 (1987) (Original)
  2. G.J.S. Cooper, A.C. Willis, A. Clark, R.C. Turner, R.B. Sim and K.B.M. Reid, Proc. Natl. Acad. Sci. USA, 84, 8628 (1987) (Original; Complete Sequence of Amylin)
  3. A. Clark, G.J.S. Cooper, C.E. Lewis, F.J. Morris, A.C. Willis, K.B.M. Reid and R.C. Turner, Lancet, 2, 231 (1987) (Pathologics)

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