Big Endothelin-3 (Human, 1 – 41 Amide)

215,00 € excl. 19% VAT

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SKU: 4223-s Category:

Big Endothelin-3 (Human, 1 – 41 Amide)

4223-s 0.1 mg | 215.00 EUR

Synthetic Product (disulfide bonds between Cys1-Cys15 and Cys3-Cys11)

Cys – Thr – Cys – Phe – Thr – Tyr – Lys – Asp – Lys – Glu – Cys – Val – Tyr – Tyr – Cys – His – Leu – Asp – Ile – Ile – Trp – Ile – Asn – Thr – Pro – Glu – Gln – Thr – Val – Pro – Tyr – Gly – Leu – Ser – Asn – Tyr – Arg – Gly – Ser – Phe – Arg -NH2

(M.W. 4923.5) C223H322N56O63S4

The purity of Big Endothelin-3 (Human, 1 – 41 Amide) is guaranteed to be higher than 99% by HPLC

Big Endothelin-3 (Human, 1 – 41 Amide) is the percursor for ET-3 and is expressed in intestinal epithelial cells, kidney and brain neurons.

The biological activity of our peptide Big ET-3 is examined by the Division of Pharmacology, Peptide Institute, Inc.

References:

  1. K.D. Bloch, R.L. Eddy, T.B. Shows and T. Quertermous, J. Biol. Chem, 264, 18156 (1989) (Original; cDNA)
  2. T. Kosaka, N. Suzuki, Y. Ishibashi, H. Matsumoto, Y. Itoh, S. Ohkubo, K. Ogi, C. Kitada, H. Onda and M. Fujino, J. Biochem, 116, 443 (1994) (Biosynthesis)

Big Endothelin-3 (Human, 1 – 41 Amide) is distributed through Peptide Institute, Inc. under the license of Takeda Pharmaceutical Company, Ltd.

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