Big Gastrin I (Human)

115,00 € excl. 19% VAT

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SKU: 4183 Category:

Big Gastrin I (Human)

4183-s 0.1 mg | 115.00 EUR
4183-v 0.5 mg | 445.00 EUR

Pyr – Leu – Gly – Pro – Gln – Gly – Pro – Pro – His – Leu – Val – Ala – Asp – Pro – Ser – Lys – Lys – Gln – Gly – Pro – Trp – Leu – Glu – Glu – Glu – Glu – Glu – Ala – Tyr – Gly – Trp – Met – Asp – Phe – NH2

(M.W. 3849.2) C176H251N43O53S [60675-77-6]

Synthetic Product (Ammonium Form) | The purity is guaranteed to be higher than 99% by HPLC

Big-Gastrin I, a 36 mer polypeptide, is produced in vivo together with other gastrin peptides from the precursor peptide, progastrin. Big Gastrin is a stimulator for the parietal cells of the stomach and for the production of pancreatic enzymes.

References:

  1. A.M. Choudhury, G.W. Kenner, S. Moore, K.L. Ramachandran, W.D. Thorpe, R. Ramage, G.J. Dockray, R.A. Gregory, L. Hood and M. Hunkapiller, Hoppe-Seyler’s Z. Physiol. Chem., 361, 1719 (1980) (Original with Chem. Synthesis of Big Gastrin)
  2. Handbook of Experimental Pharmacology,Secretin, Cholecystokinin, Pancreozymin and Gastrin,(J.E. Jorpes and V. Mutt, eds.), Springer-Verlag, Berlin Vol.: 34, (1973) (Gastrin; Review)

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