CA-074 Me

135,00 € excl. 19% VAT

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CA-074 Me

4323-v 5 mg | 135.00 EUR

(L- 3- trans- (Propylcarbamoyl)oxirane- 2- Carbonyl)- L- Isoleucyl- L- Proline Methyl Ester

(M.W. 397.47) C19H31N3O6 [147859-80-1]

Synthetic Product

Inhibitor for Cathepsin B

The methyl ester of CA-074 is a very potent and selective irreversible cell permeable inhibitor for cathepsin B. The biologically active inhibitor is released after hydrolysis of the ester by intracellular esterases. Therefore, CA-074 Me is working only in vivo and whole cell experiments, but not in in vitro experiments.

Download PDF Data Sheet:    pdf

References:

  1. D.J. Buttle, M. Murata, C.G. Knight, and A.J. Barrett, Arch. Biochem. Biophys., 299, 377 (1992) (Original)

Links to publications that use our inhibitor CA-074 Me | code 4323-v:

  1. Lysosome-Dependent Activation of Human Dendritic Cells by the Vaccine Adjuvant QS-21

CA-074 Me is distributed through Peptide Institute, Inc. under the license of Taisho Pharmaceutical Co., Ltd.

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