µ-Conotoxin GIIIB

385,00 € excl. 19% VAT

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µ-Conotoxin GIIIB
(Marine Snail, Conus geographus)

4217-v 0.5 mg | 385.00 EUR

Synthetic Product (disulfide bonds between Cys3-Cys15, Cys4-Cys20 and Cys10-Cys21)

Arg – Asp – Cys – Cys – Thr – Hyp – Hyp – Arg – Lys – Cys – Lys – Asp – Arg – Arg – Cys – Lys – Hyp – Met – Lys – Cys – Cys – Ala – NH2

(M.W. 2640.2) C101H175N39O30S7

The purity is guaranteed to be higher than 99% by HPLC

Na+ Channel Blocker; Specific for Skeletal Muscle

The biological activity of this peptide is examined by the Division of Pharmacology, Peptide Institute, Inc.

Important information:
µ-Conotoxin GIIIB can be shipped to autorized endusers with own application labs only. We will need a dedicated end user declaration for this item and cannot ship conotoxin to trading companies!

References:

  1. S. Sato, H. Nakamura, Y. Ohizumi, J. Kobajashi and Y. Hirata, FEBS Lett., 155, 277 (1983) (Original)
  2. L.J. Cruz, W.R. Gray, B.M. Olivera, R.D. Zeikus, L. Knerr, D. Yoshikami and E. Mocyzydlowski, J. Biol. Chem., 260, 9280 (1985) (Naming
  3. Y. Ohizumi, H. Nakamura, J. Kobajashi and W.A. Catteral, J. Biol. Che., 261, 6149 (1986) (Pharmacol)
  4. S. Kubo, N. Chino, T.X. Watanabe, T. Kimura and S. Sakakibara, Pept. Res., 6, 66 (1993) (Chem. Synthesis and Pharmacol.)

Links to publications that use our peptide µ-Conotoxin GIIIB | code 4217-v:

  1. Ursachen der Insulin- und Katecholamin-induzierten Membranhyperpolarisation am Skelettmuskel

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