omega-Conotoxin GVIA

315,00 € excl. 19% VAT

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ω-Conotoxin GVIA
omega-Conotoxin GVIA

(Marine Snail, Conus geographus)

4161-v 0.5 mg | 315.00 EUR

Synthetic Product (disulfide bonds between Cys1-Cys16, Cys8-Cys19 and Cys15-Cys26)

Cys – Lys – Ser – Hyp – Gly – Ser – Ser – Cys – Ser – Hyp – Thr – Ser – Tyr – Asn – Cys – Cys – Arg – Ser – Cys – Asn – Hyp – Tyr – Thr – Lys – Arg – Cys – Tyr – NH2

(M.W. 3037.3) C120H182N38O43S6 [106375-28-4]

The purity is guaranteed to be higher than 99% by HPLC

N-type Ca2+ Channel Blocker

The biological activity of our peptide toxin omega-Conotoxin GVIA is examined by the Division of Pharmacology, Peptide Institute, Inc.

Important information:
ω-Conotoxin GVIA can be shipped to autorized end users with own application labs only. We will need a dedicated end user declaration for this item and cannot ship conotoxin to trading companies!

References:

  1. B.M. Olivera, J.K.McIntosh, L.J. Cruz, F.A. Luque, and W.R. Gray, Biochemistry, 23, 5087 (1984) (Original)
  2. Y. Nishiuchi, K.Y. Kumagaye, Y. Noda, T.X. Watanabe and S. Sakakibara, Biopolymers, 25, S61 (1986) (Chem. Synthesis and S-S Bond)

Links to publications that use our peptide ω-Conotoxin GVIA | code 4161-v:

  1. Altered synaptic transmission at olfactory and vomeronasal nerve terminals in mice lacking N-type calcium channel Cav2.

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