µ-Conotoxin SIIIA

310,00 € excl. 19% VAT

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µ-Conotoxin SIIIA
(Marine Snail, Conus striatus)

4440-v 0.5 mg | 310.00 EUR

Synthetic Product (disulfide bonds between Cys3-Cys13, Cys4-Cys19 and Cys8-Cys20)

Pyr – Asn – Cys – Cys – Asn – Gly – Gly – Cys – Ser – Ser – Lys – Trp – Cys – Arg – Asp – His – Ala – Arg – Cys – Cys – NH2

(M.W. 2207.5) C83H123N33O27S6

The purity is guaranteed to be higher than 99% by HPLC

Na+ Tetrodotoxin-Resistant Na+ Channel Blocker with analgesic activity
µ-Conotoxin SIIIA might be a potential research tool for efficient pain modulation.

Important information:
µ-Conotoxin SIIIA can be shipped to autorized end users with own application labs only. We will need a dedicated end user declaration for this item and cannot ship conotoxin to trading companies!

References:

  1. G. Bulaj, P.J. West, J.E. Garrett, M. Marsh, M.M. Zhang, R.S. Norton, B.J. Smith, D. Yoshikami and B.M.Olivera, Biochemistry, 44, 7259 (2005) (Original)
  2. S. Yao, M.M. Zhang, D. Yoshikami, L. Azam, B.M. Olivera, G. Bulaj and R.S. Norton, Biochemistry, 47, 10940 (2008)
  3. C.Z. Wang, H. Zhang, H. Jiang, W. Lu, Z.Q. Zhao and C.W. Chi, Toxicon, 47, 122 (2006) (Pharmacol)
  4. B.R. Green, P. Catlin, M.M. Zhang, B. Fiedler, W. Bayudan, A. Morrison, R.S. Norton, B.J. Smith, D, Yoshikami, B.M.Olivera and G. Bulaj, Chem Biol., 14, 399 (2007) (Pharmacol.)

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