Dermcidin-1L (Human)

180,00 € excl. 19% VAT

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SKU: 4454-s Category:

Dermcidin-1L (Human)
DCD-1L (Human)

4454-s 0.1 mg | 180.00 EUR

Synthetic Product

Ser- Ser- Leu- Leu- Glu- Lys- Gly- Leu- Asp- Gly- Ala- Lys- Lys- Ala- Val- Gly- Gly- Leu- Gly- Lys- Leu- Gly- Lys- Asp- Ala- Val- Glu- Asp- Leu- Glu- Ser- Val- Gly- Lys- Gly- Ala- Val- His- Asp- Val- Lys- Asp- Val- Leu- Asp- Ser- Val- Leu

(M.W. 4818.4) C210H359N57O71

The purity of our antimicrobial peptide Dermcidin-1L | DCD-1L is guaranteed to be higher than 99% by HPLC

Dermcidin-1L is an antimicrobial peptide found in human sweat. It was reported that in studies usind DCD-1L, Dermcidin-1L was active against Gram-positive and negative bacteria and fungus. Dermcidin-1L activates human keratinocytes.
DCD-1L does not show membrane permeability.

References:

  1. B. Schittek, R. Hipfel, B. Sauer, J. Bauer, H. Kalbacher, S. Stevanovic, M. Schirle, K. Schroeder, N. Blin, F. Meier, G. Rassner C. Garbe, Nat. Immunol. 2, 1133 (2001) (Original; antimicrobial peptide)
  2. S. Rieg, H. Steffen, S. Seeber, A. Humeny, H. Kalbacher, K. Dietz, C. Garbe and B. Schittek, J. Immunol. 174, 8003 (2005) (endogenous form)
  3. H. Steffen, S.Rieg, I. Wiedemann, H. Kalbacher, M. Deeg, H.-G. Sahl, A. Peschel, F. Götz, C. Garbe and B. Schittek, Antimicrob. Agents Chemother., 50, 2608 (2006) (Pharmacol)
  4. F. Niyonsaba, A. Suzuki, H. Ushio, I. Nagaoka, H. Ogawa and K. Okumura, Br. J. Dermatol, 160, 243 (2009) (Pharmacology)
  5. I. Senyurek, M. Paulmann, T. Sinnberg, H. Kalbacher, M. Deeg, T. Gutsmann, M. Hermes, T. Kohler, F. Götz, C. Wolz, A. Peschel and B. Schittek, Antimicrob. Agents Chemother., 53, 2499 (2009) (Pharmacology)

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