Des-Acyl Ghrelin (Human)

105,00 € excl. 19% VAT

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SKU: 4436-s Category:

Des-Acyl Ghrelin (Human)
Des-n-Octanoyl Ghrelin (Human)

4436-s 0.1 mg | 105.00 EUR

Gly – Ser – Ser – Phe – Leu – Ser – Pro – Glu – His – Gln – Arg – Val – Gln – Gln – Arg – Lys – Glu – Ser – Lys – Lys – Pro – Pro – Ala – Lys – Leu – Gln – Pro – Arg

(M.W. 3244.7) C141H235N47O41

Synthetic Product (Trifluoracetate Form)

The purity of Des-Acyl Ghrelin (Human) is guaranteed to be higher than 99% by HPLC

Des-Octanoylated Ghrelin with Distinct Effect on Food Intake

The fatty acid acylation of ghrelin seems to be essential for the strong GH-releasing activity. The Non-acylated form Des-n-Octanoyl Ghrelin does not bind to the ghrelin receptor and did not induce growth hormone release. Des-Acyl Ghrelin shows inotropic effects in papillary muscle and cardioprotective activity.

References:

  1. M. Kojima, H. Hosoda, Y. Date, M. Nakazato, H. Matsuo and K. Kangawa, Nature, 402, 656 (1999) (Original)

The peptide Des-n-Octanoyl Ghrelin (Human) is distributed through Peptide Institute, Inc. under the license of Dr. K. Kangawa

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