Exendin (5-39)

260,00 € excl. 19% VAT

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SKU: 4345-v Category:

Exendin (5-39)
(Lizard, Heloderma horridum)

4345-v 0.5 mg | 260.00 EUR

Thr – Phe – Thr – Ser – Asp – Leu – Ser – Lys – Gln – Met – Glu – Glu – Glu – Ala – Val – Arg – Leu – Phe – Ile – Glu – Trp – Leu – Lys – Asn – Gly – Gly – Pro – Ser – Ser – Gly – Ala – Pro – Pro – Pro – Ser – NH2

(M.W. 3806.2) C169H262N44O54S

Synthetic Product

The purity is guaranteed to be higher than 99% by HPLC

GLP-1 Receptor Antagonist

Exendin (5-39) is described as an antagonist of glucagon-like peptide 1 (GLP-1) receptors.
Infusion of exendin (5-39) and Amyloid-beta-Protein (human, 1-40) into the rat brain indicated a functional role of endogenous GLP-1 in beta-amyloid protein-induced neurotoxicity.

Our chemically synthesized peptide Exendin (5-39) will be shipped at room temperature. Long term storage is recomended in a freezer at – 18 degrees.

References:

  1. C. Montrose-Rafizadeh, H. Yang, B.D. Rodgers, A. Beday, L.A. Pritchette and J. Eng, J. Biol. Chem, 272, 21201 (1997) (Original; Potent Antagonist)

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