Fibronectin Active Fragment (GRGDS)

30,00 € excl. 19% VAT

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SKU: 4189 Category:

Fibronectin Active Fragment (GRGDS)

4189-v 0.5 mg | 30.00 EUR

Gly-Arg-Gly-Asp-Ser

(M.W. 490.47) C17H30N8O9 [96426-21-0]

4189-25 mg | 225.00 EUR
4189-100 mg | 575.00 EUR

Gly-Arg-Gly-Asp-Ser · ½AcOH · 2H2O

(M.W. 490.47) · 30.03 · 36.03 C17H30N8O9 · ½CH3COOH · 2H2O

Synthetic Product

The purity is guaranteed to be higher than 99% by HPLC

Fibronectin Fragment Gly-Arg-Gly-Asp-Ser (GRGDS) seems to be a critical factor for cellinteraction with fibronectin. GRGDS was successful used as inhibitor for melanoma cells in a mice model.

References:

  1. S.K. Akiyama and K.M. Yamada, J. Biol. Chem, 260, 10402 (1985) (Original description of Fibronectin Active Fragment (GRGDS))
  2. K. Olden, S. Mohla, S.A. Newton, S.L.White and M.J. Humphries, Ann. N. Y. Acad. Sci., 551, 421 (1988) (Review)

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