Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2

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Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2

MocAc-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2
[NFF-2]

3167-v 1 mg | 75.00 EUR

(7-Methoxycoumarin-4-yl)acetyl- L-arginyl- L-prolyl- L-lysyl- L-prolyl- L-tyrosyl- L-alanyl- L-norvalyl- L-tryptophyl- L-methionyl- Nε– (2,4-dinitrophenyl)- L-lysine amide

(M.W. 1656.90) C79H105N19O19S [158584-08-8]

Synthetic Product
Purity Grade B: Contamination of less than 4% might be detectable by HPLC

Fluorescence-Quenching Substrate for Matrix Metalloproteinases

The Fluorescence-Quenching Substrate Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 was hydrolized rapidly by MMP-3 (stromelysin 1) whereas interstitial collagenase (MMP-1) cleaved this substrate much slower.

References:

  1. H. Nagase, C.G. Fields and G.B. Fields, J. Biol. Chem., 269, 20952 (1994)

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