MOCAc-Lys-Pro-Leu-Gly-Leu-A₂pr(DNP)-Ala-Arg-NH2

3226-v 1 mg | 110.00 EUR

(7-Methoxycoumarin-4-yl)acetyl- L-lysyl- L-prolyl- L-leucyl- glycyl- L-leucyl- [N^β-(2,4- dinitrophenyl)- L-2,3-diaminopropionyl]- L-alanyl- L-arginine amide

Synthetic Product (Trifluoracetate Form)
A trace of impurity might be detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 2 %.

Fluorescence-Quenching Substrate for Matrix Metalloproteinases and ADAM-17 / Tumor Necrosis Factor Converting Enzyme (TACE)

MOCAc-Lys-Pro-Leu-Gly-Leu-A₂pr(DNP)-Ala-Arg-NH2 is a commonly used Fluorescence-Quenching Substrate from MCA / DNP type.

References:

1. U. Neumann, H. Kubota, K. Frei, V. Ganu and D. Leppert, Anal. Biochem., 328, 166 (2004)
2. A. Trifilieff, C. Walker, T. Keller, G. Kottirsch and U. Neumann, Br. J. Pharmacol., 135, 1655 (2002)
3. M.C. Riitano, H. Pfister, P. Engelhardt, U. Neumann, M. Reist, A. Zurbriggen, M. Stoffel, J. Peel, T. Jungi, P. Schawalder and D.E. Spreng, Am. J. Vet. Res., 63, 1423 (2002)