Muscarinic Toxin 1

230,00 € excl. 19% VAT

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Muscarinic Toxin 1
MT1; MTX1;
(Green Mamba, Dendroaspis angusticeps)

4341-s 0.1 mg | 230.00 EUR

Leu – Thr – Cys – Val – Thr – Ser – Lys – Ser – Ile – Phe – Gly – Ile – Thr – Thr – Glu – Asn – Cys – Pro – Asp – Gly – Gln – Asn – Leu – Cys – Phe – Lys – Lys – Trp – Tyr – Tyr – Ile – Val – Pro – Arg – Tyr – Ser – Asp – Ile – Thr – Trp – Gly – Cys – Ala – Ala – Thr – Cys – Pro – Lys – Pro – Thr – Asn – Val – Arg – Glu – Thr – Ile – Arg – Cys – Cys – Glu – Thr – Asp – Lys – Cys – Asn – Glu

(M.W. 7509.5) C326H499N87O101S8

Synthetic Product (disulfide bonds between Cys3– Cys24, Cys17– Cys42, Cys46– Cys58 and Cys59– Cys64 )

The purity of muscarinic toxin 1 code 4341-s is guaranteed to be higher than 99% by HPLC

Agonist for Muscarinic Acetylcholine Receptor-1 (M1)

References:

  1. A. Adem and E. Karlsson, Life Sci., 60, 1069 (1997) (Original)
  2. H. Nishio, Y. Nishiuchi, T. Inui, K.N. Bradley, A.L. Harvey and T. Kimura, Peptide Science 1999, 125 (2000) (S-S Bond)
  3. M. Jolkkonen, A. Adem, U. Hellman, C. Wernstedt and E. Karlsson, Toxicon, 33, 399 (1995) (Original; Structure)
  4. Z. D. Jerusalinsky and A.L. Harvey, Trends Pharmacol. Sci., 15, 424 (1994) (Review; Toxin for Muscarinic Receptor)

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