Muscarinic Toxin α

230,00  excl. 19% VAT

Muscarinic Toxin α
Muscarinic Toxin Alpha | MTα
(Black Mamba, Dendroaspis polylepis)

4424-s 0.1 mg | 230.00 EUR

Leu – Thr – Cys – Val – Thr – Ser – Lys – Ser – Ile – Phe – Gly – Ile – Thr – Thr – Glu – Asn – Cys – Pro – Asp – Gly – Gln – Asn – Leu – Cys – Phe – Lys – Lys – Trp – Tyr – Tyr – Leu – Asn – His – Arg – Tyr – Ser – Asp – Ile – Thr – Trp – Gly – Cys – Ala – Ala – Thr – Cys – Pro – Lys – Pro – Thr – Asn – Val – Arg – Glu – Thr – Ile – His – Cys – Cys – Glu – Thr – Asp – Lys – Cys – Asn – Glu

(M.W. 7545.4) C326H491N89O102S8

Synthetic Product (disulfide bonds between Cys3– Cys24, Cys17– Cys42, Cys46– Cys58 and Cys59– Cys64 )

The purity of muscarinic toxin alpha is guaranteed to be higher than 99% by HPLC

Ligand for Muscarinic Acetylcholine Receptor-3/5 (M3/M5) (Non-specific Ligand)

References:

  1. M. Jolkkonen, P.L.M. van Giersbergen, U. Hellman, C. Wernstedt, A. Oras, N. Satyapan, A. Adem and E. Karlsson, Eur. J. Biochem., 234, 579 (1995) (Original)
  2. M. Jolkkonen, A. Oras, T. Toomela, E. Karlsson, J. Järv and K.E.O. Akerman, Toxicon, 39, 377 (2001) (Pharmacol; Mechanism of Receptor Binding)