Neuromedin B

35,00 € excl. 19% VAT

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SKU: 4152 Category:

Neuromedin B
(Human, Porcine, Rat)

4152-v 0.5 mg 35.00 EUR
4152 1.0 mg 49.00 EUR

Gly – Asn – Leu – Trp – Ala – Thr – Gly – His – Phe – Met – NH2

(M.W. 1132.3) C52H73N15O12S [87096-84-2]

4152-25 mg | 495.00 EUR

Gly – Asn – Leu – Trp – Ala – Thr – Gly – His – Phe – Met – NH2 · AcOH · 5H2O

(M.W. 1132.3) · 60.05 · 90.08 C52H73N15O12S · CH3COOH · 5H2O

Synthetic Product | The purity is guaranteed to be higher than 99% by HPLC

The 10 mer peptide Neuromedin B was originally isolated from porcine spinal cord and is highly concentrated in rat pituitary gland. This mammalian peptide belongs to the bombesin like peptide family and seems to act as an autocrine/paracrine inhibitor of thyrotropin (TSH) release.

The biological activity of Neuromedin B is examined by the Division of Pharmacology, Peptide Institute, Inc.

References:

  1. N. Minamino, K. Kangawa and H. Matsuo, Biochem. Biophys. Res. Commun., 114, 541 (1983) (Original; Neuromedin B Porcine)
  2. I.M. Krane, S.L. Naylor, D. Helin-Davis, W.W. Chin, E.R. Spindel, J. Biol. Chem, 263, 13317 (1988) (cDNA Seq.; Neuromedin B Human)
  3. E. Wada, J. Way, A.M. Lebacq-Verheyden, J.F. Battey, J. Neurosci., 10, 2917 (1990) (cDNA Seq.; Neuromedin B Rat)

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