Neurotoxin NSTX-3

85,00 € excl. 19% VAT

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SKU: 4195-s Category:

Neurotoxin NSTX-3
(Papua New Guinean Spider, Nephila maculata)

4195-s 0.1 mg | 85.00 EUR

The spider Neurotoxin NSTX-3 is a specific Na+ channel blocker, which inhibits glutamate and postsynaptic potentials as well. NSTX-3 from PeptaNova is a synthetic product and not isolated from animal origin.

2,4- Dihydroxyphenylacetyl- L- Asparaginyl- Ni– (L- Arginyl- Putreanyl)- Cadaverine

(M.W. 664.80) C30H52N10O7

Synthetic Product

The purity is guaranteed to be higher than 99% by HPLC

References:

  1. RY. Aramaki, T. Yasuhara, T. Higashijima, M. Yoshioka, A. Miwa, N. Kawai and T. Nakajima, Proc. Jpn. Acad., 62 (B), 359 (1986) (Original)
  2. T. Teshima, T. Wakamiya, Y. Aramaki, T. Nakajima, N. Kawai and T. Shiba, Tetrahedron Lett., 28, 3509 (1987) (Chem. Synthesis Preliminary)
  3. T. Teshima, T. Matsumoto, T. Wakamiya, T. Shiba, Y. Aramaki, T. Nakajima and N. Kawai, Tetrahedron Lett., 47, 3305 (1991) (Chem. Synthesis; Total Synthesis)

This peptide is distributed through Peptide Institute, Inc. under the license of Takeda Pharmaceutical Company , Ltd.

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