Platelet Factor-4 (Human, 58 – 70)

35,00  excl. 19% VAT

SKU: 4305-v Category:

Platelet Factor-4 (Human, 58 – 70)
PF4 (58-70) (human)

4305-v 0.5 mg | 35.00 EUR

Pro – Leu – Tyr – Lys – Lys – Ile – Ile – Lys – Lys – Leu – Leu – Glu – Ser

(M.W. 1573.0) C76H133N17O18 [82989-21-7]

Synthetic Product

The purity is guaranteed to be higher than 99% by HPLC

Angiogenesis Inhibitor

Platelet Factor-4 (Human, 58 – 70) is an active inhibitor of angiogenesis in the chicken chorioallantoic membrane. Similiar to the compleat platelet factor, its C-terminal tridecapeptide with the sequence (58-70) is working as a potent immunosuppressor in mice models.

References:

  1. T.E. Maione, G.S. Gray, J. Petro, A.J. Hunt, A.L. Donner, S.I. Bauer, H.F. Carson, and R.J. Sharpe, Science, 247, 77 (1990) (Original)
  2. M.B.Zucker et al., Proc. Natl. Acad. Sci. USA, 86, 7571 (1989)