Ser-Gln-Asn-Tyr-Pro-Ile-Val

H-Ser-Gln-Asn-Tyr-Pro-Ile-Val-OH

4236-v 5 mg | 125.00 EUR

H- Ser- Gln- Asn- Tyr- Pro- Ile- Val- OH

Synthetic Product
A single spot is detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 1 %.

Substrate for HIV-1 Protease

The sequence (H-Ser-Gln-Asn-Tyr-Pro-Ile-Val-OH) of this synthetic heptapeptide substrate is identical to the partial sequence p17-p24 in the gag polyprotein.

References:

1. S. Billich, M.-T. Knoop, J. Hansen, P. Strop, J. Sedlacek, R. Mertz and K. Moelling, J. Biol. Chem., 263, 17905 (1988) (Original)
2. P.L. Darke, R.F. Nutt, S.F. Brady, V.M. Garsky, T.M. Ciccarone, C.-T. Leu, P.K. Lumma, R.M. Freidinger, D.F. Veber and I.S. Sigal, Biochem. Biophys. Res. Commun., 156, 297 (1988) (Original)
3. P.L. Darke, C-T. Leu, L.J. Davis, J.C. Heimbach, R.E. Diehl, W.S. Hill, R.A.F. Dixon and I.S. Sigal, J. Biol. Chem., 264, 2307 (1989) (Biochem.)