β-Sheet Breaker Peptide iAβ5

155,00 € excl. 19% VAT

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SKU: 4358-v Category:

β-Sheet Breaker Peptide iAβ5

4358-v 5 mg | 155.00 EUR

Synthetic Product (Trifluoroacetate Form)

H-Leu-Pro-Phe-Phe-Asp-OH

(M.W. 637.72) C33H43N5O8

The purity is guaranteed to be higher than 99% by HPLC

Inhibitor of Amyloid Deposition

The pentapeptide beta-Sheet Breaker Peptide iAβ5 is known to inhibit amyloidogenesis in rat brain models. It disassembles preformed fibrils and reduces amyloid beta-protein deposition in vivo. beta-Sheet Breaker Peptide may be an interesting tool in finding new therapeutic aspects in Alzheimer’s disease research.

References:

  1. C. Soto, E.M. Sigurdsson, L. Morelli, R.A. Kumar, E.M. Castano, and B. Frangione, Nat. Med., 4, 822 (1998) (Original; Pharmacol.)

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