Tityustoxin K alpha

285,00 € excl. 19% VAT

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SKU: 4313-s Category:

Tityustoxin K alpha
TsTX-Kα
(Scorpion, Tityus serrulatus)

4313-s 0.1 mg | 285.00 EUR

Val – Phe – Ile – Asn – Ala – Lys – Cys – Arg – Gly – Ser – Pro – Glu – Cys – Leu – Pro – Lys – Cys – Lys – Glu – Ala – Ile – Gly – Lys – Ala – Ala – Gly – Lys – Cys – Met – Asn – Gly – Lys – Cys – Lys – Cys – Tyr – Pro

(M.W. 3941.7) C168H275N49O46S7

Synthetic Product (Disulfide bonds undetermined)

The purity is guaranteed to be higher than 99% by HPLC

Tityustoxin K alpha, a Voltage-Dependent K+ Channel (A Channel) Blocker

Tityustoxin K alpha offered from PeptaNova is a synthetic peptide toxin originally isolated from the venom of the scorpion, Tityus serrulatus. It is an interesting Voltage-Dependent K+ Channel (A Channel) Blocker and shows additionally effects on the release of dopamine and acetylcholine in rat brain.

Shipping | Storage | Stability
Our product Tityustoxin K alpha (TsTX-Kα) will be shipped at room temperature. Information about product specific storage conditions will be found on the vial. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing by preparing aliquots.

References:

  1. T.R. Werkman, T.A. Gustafson, R.S. Rogowski, M.P. Blaustein and M.A. Rogawski, Mol. Pharmacol., 44, 430 (1993) (Original)
  2. R.S. Rogowski, B.K. Krueger, J.H. Collins and M.P. Blaustein, Proc. Natl. Acad. Sci. USA, 91, 1475 (1994) (Pharmacol.)
  3. T.A.A. Casali, R.S. Gomez, T. Moraes-Santos and M.V Gomez, Neuropharmacology, 34, 599 (1995) (Pharmacon.)
  4. W.F. Hopkins, J. Pharmacol. Exp. Ther, 285, 1051 (1995) (Pharmacol.)

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