TMRIA-K4
Fluorophore Peptide in Coiled-Coil Tag-Probe Labeling System

3401-v 10 µg | 165.00 EUR

Synthetic Product (Trifluoracetate)

S-[2-({4- [3,6-Bis(dimethylamino)xanthylium-9-yl]- 3- carboxyphenyl}amino)-2-oxoethyl]-Cys-(Lys-Ile-Ala-Ala-Leu-Lys-Glu)₄

The purity is guaranteed to be higher than 99% by HPLC

The "coiled-coil tag-probe system was developed from Professor Matsuzaki of Kyoto University. In close collaboration with Professor Matsuzaki, Peptide Institute could offer TMRIA-K4 [TMRIA = tetramethylrhodamine-5-iodoacetamide] which is a synthetic analog of TMR-K4. In contrast to this peptide, the fluorophore functionality of TMRIA-K4 was introduced via the side chain SH group of the Cys residue at the N-terminus of K4. The compatible characteristics to TMR-K4 have been confirmed.
TMRIA-K4 should be a useful alternative to the originally designed peptide and is now available in Europe via PeptaNova.

References:

1. Y. Yano, A. Yano, S. Oishi, Y. Sugimoto, G. Tsujimoto, N. Fujii, and K. Matsuzaki,ACS Chem. Biol., 3, 341 (2008)(TMR-K4; Reference Paper to TMRIA-K4)

The fluorophore peptide TMRIA-K4 is distributed through Peptide Institute, Inc. under the license of Kyoto University.