Vasoactive Intestinal Contractor Peptide (Mouse)

98,00 € excl. 19% VAT

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SKU: 4211-s Category:

Vasoactive Intestinal Contractor Peptide (Mouse)
VIC (Mouse) | Endothelin-2 (Mouse, Rat)

4211-s 0.1 mg | 98.00 EUR

Synthetic Product (disulfide bonds between Cys1-Cys15 and Cys3-Cys11)

Cys – Ser – Cys – Asn – Ser – Trp – Leu – Asp – Lys – Glu – Cys – Val – Tyr – Phe – Cys – His – Leu – Asp – Ile – Ile – Trp

(M.W. 2573.9) C116H161N27O32S4 [138863-63-5]

The purity is guaranteed to be higher than 99% by HPLC

The biological activity of this peptide is examined by the Division of Pharmacology, Peptide Institute, Inc.

Vasoactive Intestinal Contractor Peptide | VIC belongs to the endothelin family (Endothelin-2) and seems to act as a gastrointestinal hormone. The sequence is very silmiliar to that of Endothelin-1. They differ is only 3 amino acids. The in vivo contractor activity of the Vasoactive Intestinal Contractor VIC is higher than that of Endothelin, but compared with lower vasoconstictor activities.

References:

  1. N. Ishida, K. Tsujioka, M. Tomoi, K. Saida and Y. Mitsui, FEBS Lett., 247, 337 (1989) (Original)
  2. K. Saida, Y. Mitsui and N. Ishida, J. Biol. Chem., 264, 14613 (1989) (Original, Nucleotide Sequence)

This peptide is distributed through Peptide Institute, Inc. under the license of Takeda Pharmaceutical Company, Ltd. and the National Institute of Advanced Industrial Scienence & Technology (AIST)

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