Z-Ala-Ala-Asn-AMC

45,00 € excl. 19% VAT

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Z-Ala-Ala-Asn-AMC

Z-AAN-AMC | Z-Ala-Ala-Asn-MCA

3209-v 5 mg | 45.00 EUR

Benzyloxycarbonyl- L-alanyl- L-alanyl- L-asparagine- 4-methylcoumaryl-7-amide

(M.W. 565.57) C28H31N5O8 [149697-16-5]

Synthetic Product
A trace of impurity might be detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 2 %.

Z-Ala-Ala-Asn-AMC is a fluorogenic substrate for Legumain

References:

  1. J.-M. Chen, P.M. Dando, N.D. Rawlings, M.A. Brown, N.E. Young, R.A. Stevens, E. Hewitt, C. Watts and A.J. Barrett, J. Biol. Chem, 272, 8090 (1997)
  2. B. Manoury, E.W. Hewitt, N. Morrice, P.M. Dando, A.J. Barrett and C. Watts, Nature, 396, 695 (1998)
  3. S.J. Choi, S.V. Reddy, R.W. Devlin, C. Menaa, H. Chung, B.F. Boyce and G.D. Roodman, J. Biol. Chem., 274, 27747 (1999)
  4. P.M. Dando, M. Fortunato, L. Smith, C.G. Knight, J.E. McKendrick and A.J. Barrett, Biochem. J., 339, 743 (1999)

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