Z-Arg-Arg-AMC

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Z-Arg-Arg-AMC

Z-RR-AMC | Z-Arg-Arg-MCA

3123-v 5 mg | 35.00 EUR

Benzyloxycarbonyl- L-arginyl- L-arginine- 4-methylcoumaryl-7-amide

(M.W. 621.70) C30H39N9O6 [88937-61-5]

Synthetic Product (Hydrochloride Form)
A trace of impurity might be detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 2 %.

Substrate for Cathepsin B

The benzyloxycarbonyl protected dipeptide Z-Arg-Arg-AMC is used as high sensitive and selective fluorogenic enzyme substrate for the determination of Cathepsin B. (MCA is used in Japan as synonym for AMC)

References:

  1. A.J. Barrett and H. Kirschke, Methods in Enzymology, Proteolytic Enzymes Part C,(L. Lorand, ed.), Academic Press, New York, Vol. 80, pp. 535-561 (1981)

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