(Z-LL)2 Ketone

68,00 € excl. 19% VAT

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(Z-LL)2 Ketone | (Z-Leu-Leu-NHCH2)2CO

3218-v 5 mg | 68.00 EUR

1,3- Bis[(benzyloxycarbonyl- L- leucyl- L- leucyl)amino]acetone

(M.W. 809.00) C43H64N6O9

Synthetic Product

Inhibitor for Signal Peptide Peptidase

(Z-LL)2 Ketone is established as a new selective Signal Peptide Peptidase inhibitor and did not block lysosomal cathepsins.

Shipping | Storage | Stability
Our product (Z-LL)2 Ketone will be shipped at room temperature. Information about product specific storage conditions will be found on the vial. Stock solutions should be stored at -20°C. Please avoid repeated freezing and thawing by preparing aliquots.

References:

  1. A. Weihofen, M.K. Lemberg, H.L. Ploegh, M. Bogyo and B. Martoglio, J. Biol. Chem., 275, 30951 (2000)
  2. A. Weihofen, K. Binns, M.K. Lemberg, K. Ashman and B. Martoglio, Science, 296,, 2215 (2002)
  3. A. Weihofen, M.K. Lemberg, E. Friedmann, H. Rueeger, A. Schmitz, P. Paganetti, G. Rovelli, and B. Martoglio, J. Biol. Chem., 278, 16528 (2003)

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