Z-Phe-Arg-AMC

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Z-Phe-Arg-AMC

Z-FR-AMC | Z-Phe-Arg-MCA

3095-v 5 mg 32.00 EUR

Benzyloxycarbonyl- L-phenylalanyl- L-arginine 4-methylcoumaryl-7-amide

(M.W. 612.69) C33H36N6O6 [65147-22-0]

Synthetic Product (Hydrochloride Form)
A trace of impurity might be detectable by TLC when 100 µg is applied to the plate. The amount of contamination detectable by HPLC is less than 2 %.

Fluorogenic substrate for Plasma Kallikrein and Cathepsin B/L

The abreviation AMC in Z-Phe-Arg-AMC stands for amino-methylcoumarine.  Z-Phe-Arg-MCA (4-methylcoumaryl-7-amide) is used in Japan as synonym for AMC

References:

  1. T. Morita, H. Kato, S. Iwanaga, K. Takada, T. Kimura and S. Sakakibara,J. Biochem., 82, 1495 (1977)
  2. A.J. Barret ,Biochem. J., 187, 909 (1980)

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