LL-37 (Human)
Cathelicidin Antimicrobial Peptide

4445-s 0.1 mg | 95.00 EUR

Synthetic Product

Leu- Leu- Gly- Asp- Phe- Phe- Arg- Lys- Ser- Lys- Glu- Lys- Ile- Gly- Lys- Glu- Phe- Lys- Arg- Ile- Val- Gln- Arg- Ile- Lys- Asp- Phe- Leu- Arg- Asn- Leu- Val- Pro- Arg- Thr- Glu- Ser

(M.W. 4493.3)

C205H340N60O53

The purity of LL-37 is guaranteed to be higher than 99% by HPLC

This human antimicrobial peptide LL-37 is derived from the C-terminus of the human cathelicidin CAP-18. It shows strong antimicrobial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis and some different virus types. The 37 amino acids containing polypeptide LL-37 can be dissolved in destilled Water according to the attached manual.

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References:

1. G.H. Gudmundsson, B. Agerberth, J. Odeberg, T. Bergman, B. Olsson and R. Salcedo, Eur. J. Biochem. 238, 325 (1996) (Original; Structure of LL-37)
2. R. Bals and J.M. Wilson, Cell. Mol. Life Sci. 60, 711 (2003) (Review)
3. M. Zanetti, J. Leukoc. Biol. 75, 39 (2004) (Review)
4. R. Lande, J. Gregorio, V. Facchinetti, B. Chatterjee, Y.-H. Wang, B. Homey, W. Cao, Y.-H. Wang, B. Su, F.O. Nestle, T. Zal, I. Mellman, J.-M. Schröder, Y.-J. Liu and M. Gilliet, Nature, 449, 564 (2007) (Pharmacology of LL-37)