Alpha-Defensin-1 (Human)
α-Defensin-1 | HNP-1 (Human Neutrophil Peptide-1)

4271-s 0.1 mg | 140.00 EUR

Synthetic Product (disulfide bonds between Cys²-Cys³⁰, Cys⁴-Cys¹⁹ and Cys⁹-Cys²⁹)

Ala – Cys – Tyr – Cys – Arg – Ile – Pro – Ala – Cys – Ile – Ala – Gly – Glu – Arg – Arg – Tyr – Gly – Thr – Cys – Ile – Tyr – Gln – Gly – Arg – Leu – Trp – Ala – Phe – Cys – Cys

 
The purity of alpha-Defensin-1 is guaranteed to be higher than 99% by HPLC

HNP-1 (Human) | Alpha-Defensin-1 (Human) is described as enogenous antimicrobial peptide and Chemoattractant for Monocytes. Human Neutrophil Peptide-1 is a potent stimulator of the expression of the genes for different types of collagen and plays a potential part in the biosynthetic and tissue remodeling responses of conjunctival fibroblasts. HNP-1 (Human) | Alpha-Defensin-1 (Human) shows characteristics like an antibiotic against a wide spectrum of infectious agents.
Alpha-Defensin-1 from Peptide Institute is from chemical synthesis and is not made by using recombinant methods.

References:

1. T. Ganz, M.E. Selstedt, D. Szklarek, S.S.L. Harwig, K. Daher, D.F. Bainton and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985) (Original description and isolation of alpha-defensin-1)
2. M.E. Selstedt, S.S.L. Harwig, T. Ganz, J.W. Schilling and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985) (Structure of HNP-1 (Human Neutrophil Peptide-1))

Links to publications that used our antimicrobial peptide HNP-1:

1. Community-acquired meticillin-resistant Staphylococcus aureus strain USA300 resists staphylococcal protein A modulation by antibiotics and antimicrobial peptides
   
2. Human alpha-defensin-1 protects cells from intoxication with Clostridium perfringens iota toxin
   

For Laboratory use only! Not for Drug Use!