Omega-Conotoxin MVIIA

Omega-Conotoxin MVIIA

395,00  excl. 19% VAT

ω-Conotoxin MVIIA
Omega-Conotoxin MVIIA

(Marine Snail, Conus magnus)

4289-v 0.5 mg | 395.00 EUR

Synthetic Product (disulfide bonds between Cys1-Cys16, Cys8-Cys20 and Cys15-Cys26)

Cys – Lys – Gly – Lys – Gly – Ala – Lys – Cys – Ser – Arg – Leu – Met – Tyr – Asp – Cys – Cys – Thr – Gly – Ser – Cys – Arg – Ser – Gly – Lys – Cys – NH2

(M.W. 2639.1) C102H172N36O32S7 [107452-89-1]

The purity is guaranteed to be higher than 99% by HPLC

Download: PDF Data Sheet

Reversible N-type Ca2+ Channel Blocker

The biological activity of this peptide is examined by the Division of Pharmacology, Peptide Institute, Inc.

Important information:
ω-Conotoxin MVIIA can be shipped to autorized end users with own application labs only. We will need a dedicated end user declaration for this item and cannot ship conotoxin to trading companies!

References:

  1. B.M. Olivera, L.J. Cruz, V. DeSantos, G.W. Le Cheminant, D. Griffin, R. Zeikus, J.K.McIntosh, R. Galyean, J. Varga, W.R. Gray and J. Rivier, Biochemistry, 26, 2086 (1987) (Original)
  2. K. Valentino, R. Newcomb, T. Gadbois, T. Singh, S. Bowersox, S. Binter, A. Justice, D. Yamashiro, B.B. Hoffman, R. Ciaranello, G. Miljanich and J. Ramachandran, Proc. Natl. Acad. Sci. USA, 90, 7894 (1993) (Pharmacol.)
  3. J. Fox, Pflügers Arch. 429, 873 (1995) (Pharmacol.)