(Marine Snail, Conus magnus)
4289-v 0.5 mg | 295.00 EUR
Synthetic Product (disulfide bonds between Cys1-Cys16, Cys8-Cys20 and Cys15-Cys26)
Cys – Lys – Gly – Lys – Gly – Ala – Lys – Cys – Ser – Arg – Leu – Met – Tyr – Asp – Cys – Cys – Thr – Gly – Ser – Cys – Arg – Ser – Gly – Lys – Cys – NH2
The purity is guaranteed to be higher than 99% by HPLC
Reversible N-type Ca2+ Channel Blocker
The biological activity of this peptide is examined by the Division of Pharmacology, Peptide Institute, Inc.
ω-Conotoxin MVIIA can be shipped to autorized end users with own application labs only. We will need a dedicated end user declaration for this item and cannot ship conotoxin to trading companies!
- B.M. Olivera, L.J. Cruz, V. DeSantos, G.W. Le Cheminant, D. Griffin, R. Zeikus, J.K.McIntosh, R. Galyean, J. Varga, W.R. Gray and J. Rivier, Biochemistry, 26, 2086 (1987) (Original)
- K. Valentino, R. Newcomb, T. Gadbois, T. Singh, S. Bowersox, S. Binter, A. Justice, D. Yamashiro, B.B. Hoffman, R. Ciaranello, G. Miljanich and J. Ramachandran, Proc. Natl. Acad. Sci. USA, 90, 7894 (1993) (Pharmacol.)
- J. Fox, Pflügers Arch. 429, 873 (1995) (Pharmacol.)