(Marine Snail, Conus magus)
4283-s 0.1 mg | 150.00 EUR
4283-v 0.5 mg | 310.00 EUR
Synthetic Product (disulfide bonds between Cys1-Cys16, Cys8-Cys20 and Cys15-Cys26)
Cys – Lys – Gly – Lys – Gly – Ala – Pro – Cys – Arg – Lys – Thr – Met – Tyr – Asp – Cys – Cys – Ser – Gly – Ser – Cys – Gly – Arg – Arg – Gly – Lys – Cys – NH2
The purity is guaranteed to be higher than 99% by HPLC
P / Q-type Ca2+ Channel Blocker
The synthetic peptide toxin omega-Conotoxin MVIIC is a P/Q-type calcium channels with high affinity. It blocks as well N-type calcium channels with low affinity. omega-Conotoxin MVIIC labeled with [125I] is used as diagnostical tool in the research of Lambert-Eaton myasthenic syndrome.
ω-Conotoxin MVIIC can be shipped to autorized end users with own application labs only. We will need a dedicated end user declaration for this item and cannot ship conotoxin to trading companies!
- R.R. Hillyard, V.D. Monje, I.M. Mintz, B.P. Bean, L. Nadasdi, J. Ramachandran, G. Miljanich, A. Azimi-Zoonooz, J.K.McIntosh, L.J. Cruz, J.S. Imperial and B.M. Olivera, Neuron, 9, 69 (1992) (Original; cDNA and Pharmacol.)
- M.E. Adams, R.A. Myers, J.S. Imperial, and B.M. Olivera, Biochemistry, 32, 12566 (1993) (Pharmacol.)
- W.A. Sather, T. Tanabe, J.F. Zhang, Y. Mori, M.E. Adams and R.W. Tsien, Neuron, 11, 291 (1993) (Pharmacol.)
- D.B. Wheeler, A. Randall and R.W. Tsien, Science, 264, 107 (1994) (Pharmacol.)