cyclo (Arg-Gly-Asp-D-Phe-Val)

50,00  excl. 19% VAT

SKU: 4304-v Category:

cyclo (Arg-Gly-Asp-D-Phe-Val)

4304-v 0.5 mg | 50.00 EUR

cyclo (Arg-Gly-Asp-D-Phe-Val)

(M.W. 574.63) C26H38N8O7 [137813-35-5]

4304-25 mg | 520.00 EUR

cyclo (Arg-Gly-Asp-D-Phe-Val) · AcOH · 2H2O

(M.W. 574.63) · 60.05 · 36.03 C26H38N8O7 · CH3COOH · 2H2O

Synthetic Product

The purity is guaranteed to be higher than 99% by HPLC

cyclo (Arg-Gly-Asp-D-Phe-Val) is a potent Angiogenesis Inhibitor. This cyclopeptide induces apoptosis and regression of distinct human tumor cells.

References:

  1. P.C. Brooks, A.M.P. Montgomery, M. Rosenfeld, R.A. Reisfeld, T. Hu, G. Klier and D.A. Cheresh, Cell, 79, 1157 (1994) (Original)
  2. M. Friedlander, C.L. Threesfeld, M. Sugita, M. Fruttiger, M.A. Thomas, S. Chang and D.A. Cheresh, Proc. Natl. Acad. Sci. USA, 93, 9764 (1996) (Pharmacology of cyclo (Arg-Gly-Asp-D-Phe-Val).)