Decorsin

220,00  excl. 19% VAT

SKU: 4269-s Category:

Decorsin

4269-s 0.1 mg | 220.00 EUR

Ala – Pro – Arg – Leu – Pro – Gln – Cys – Gln – Gly – Asp – Asp – Gln – Glu – Lys – Cys – Leu – Cys – Asn – Lys – Asp – Glu – Cys – Pro – Pro – Gly – Gln – Cys – Arg – Phe – Pro – Arg – Gly – Asp – Ala – Asp – Pro – Tyr – Cys – Glu

(M.W. 4377.8) C179H271N55O62S6

Synthetic Product (disulfide bond between Cys7-Cys15, Cys17-Cys27 and Cys22-Cys38)

The purity of the synthetic decorsin offered by PeptaNova is guaranteed to be higher than 99% by HPLC

Decorsin | Glycoprotein IIb/IIIa Antagonist, Platelet Aggregation Inhibitor

Decorsin is a polypeptide originally isolated from american Leech (Leech, Macrobdella decora). This synthetic 39 amino acid residue long RGD polypeptide strongly inhibits platelet aggregation and is much more active than other synthetic RGD peptides.

References:

  1. J.L. Seymour, W.J. Henzel, B. Nevins, J.T. Stults and R.A. Lazarus, J. Biol. Chem., 265, 10143 (1990) (Original description of Decorsin)
  2. A.M. Krezel, G. Wagner, J. Seymour-Ulmer and R.A. Lazarus, Science, 264, 1944 (1994) (S-S Bond determination in Decorsin)