Lipid A (E. coli)

Compound 506, LA-15-PP

24005-s 0.1 mg | 210.00 EUR

2-Deoxy-6-O-{2-deoxy-2-[(R)-3-(dodecanoyloxy) tetradecanoylamino]- 3- O- [(R)- 3- (tetra decanoyloxy) tetra decanoyl]- β- D-glucopyranosyl}- 3- O- [(R)- 3 -hydroxy tetra decanoyl]- 2-[(R)- 3 -hydroxy tetra decanoylamino]- α- D-glucopyranose 1,4′-diphosphate

Synthetic Product (Triethylammonium Form)

Download: PDF-structural formula

Lipid A (E. coli) is the active Principle of Endotoxin

Links to publications that use Lipid A from Peptanova:

1. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
   

References:

1. M. Imoto, S. Kusumoto, T. Shiba, E.Th. Rietschel, C. Galanos and O. Lüderitz, Tetrahedron Lett., 26, 907 (1985) (Original; Chem. Structure of Lipid A, E. coli )
2. M. Imoto, H. Yoshimura, T. Shimamoto, N. Sakaguchi, S. Kusumoto and T. Shiba, Bull. Chem. Soc. Jpn., 60, 2205 (1987) (Chem. Synthesis of Lipid A, E. coli)