Neuropeptide Y (Human, Rat)
NPY (Human, Rat)

4158-s 0.1 mg | 95.00 EUR
4158-v 0.5 mg | 265.00 EUR

Tyr – Pro – Ser – Lys – Pro – Asp – Asn – Pro – Gly – Glu – Asp – Ala – Pro – Ala – Glu – Asp – Met – Ala – Arg – Tyr – Tyr – Ser – Ala – Leu – Arg – His – Tyr – Ile – Asn – Leu – Ile – Thr – Arg – Gln – Arg – Tyr – NH₂

Synthetic Product

Neuropeptide Y (NPY) will be found in the peripheral and central nervous systems and in high concentrations in the brain cortical areas. This polypeptide, built of 36 amino acid residues, is involved in several physiological processes and plays a role in metabolic and cardiovascular deseases. NPY is also involved in the control of obesity, food intake and in the regulation of many other hormones.

This compound has some inherent instability. During storage, even under freezer conditions, a trace of impurity may become visible by TLC analysis. The amount of impurity determined by HPLC is less than 1%.

The biological activity of this peptide is examined by the Division of Pharmacology, Peptide Institute, Inc.

References:

1. C.D. Minth, S.R. Bloom, J.M. Polka and J.E. Dixon, Proc. Natl. Acad. Sci. USA, 81, 4577 (1984) (Original; Human-cDNA)
2. D. Larhammer, A. Ericsson and H. Persson, Proc. Natl. Acad. Sci. USA, 84, 2068 (1987) (Original; Rat Nucleotide Seq.)